sactown, on 18 March 2010 - 02:17 AM, said:
I have one other sort of body/fitness question to bounce off you...
For about two weeks now, I have stopped drinking coffee during the day and substituted bottled water.
I still drink 2 cups in the morning, but the two that I typically drank during the day are gone.
What is weird is that my energy is much better and more level. Fewer lows, as a bar, typically Atkins type of Cliff's Builder bar will take care of the low.
Can I attribute this all to better hydration by removing the diuretic in caffeine and boosting water intake, or is there another body system involved?
im a big fan of caffeine used properly. there is a caffeine crash that some experience. sounds like by removing the afternoon coffee's plus water increase has obviously worked for you. i'm not a doctor and nor do i play one on tv - so your second part of that question may have an adrenal response -
I found some interesting half life things on wikipedia that help you find your why - if its in your system for 5 hours, then the additional cups later in the day could be keeping you awake or at least not sleeping as well, therefore, your not as refreshed and struggling the next day with energy and repeating the same cycle. again just a thought -
Metabolism and half-life
Caffeine is metabolized in the liver into three primary metabolites: paraxanthine (84%), theobromine (12%), and theophylline (4%)
Caffeine from coffee or other beverages is absorbed by the stomach and small intestine within 45 minutes of ingestion and then distributed throughout all tissues of the body. It is eliminated by first-order kinetics. Caffeine can also be ingested rectally, evidenced by the formulation of suppositories of ergotamine tartrate and caffeine (for the relief of migraine) and chlorobutanol and caffeine (for the treatment of hyperemesis).
The half-life of caffeine —the time required for the body to eliminate one-half of the total amount of caffeine — varies widely among individuals according to such factors as age, liver function, pregnancy, some concurrent medications, and the level of enzymes in the liver needed for caffeine metabolism. In healthy adults, caffeine's half-life is approximately 4.9 hours. In women taking oral contraceptives, this is increased to 5–10 hours, and in pregnant women the half-life is roughly 9–11 hours. Caffeine can accumulate in individuals with severe liver disease, increasing its half-life up to 96 hours. In infants and young children, the half-life may be longer than in adults; half-life in a newborn baby may be as long as 30 hours. Other factors such as smoking can shorten caffeine's half-life. Fluvoxamine reduced the clearance of caffeine by 91.3%, and prolonged its elimination half-life by 11.4-fold (from 4.9 hours to 56 hours).
Caffeine is metabolized in the liver by the cytochrome P450 oxidase enzyme system (to be specific, the 1A2 isozyme) into three metabolic dimethylxanthines, each of which having its own effects on the body:
Paraxanthine (84%): Has the effect of increasing lipolysis, leading to elevated glycerol and free fatty acid levels in the blood plasma.
Theobromine (12%): Dilates blood vessels and increases urine volume. Theobromine is also the principal alkaloid in the cocoa bean, and therefore chocolate.
Theophylline (4%): Relaxes smooth muscles of the bronchi, and is used to treat asthma. The therapeutic dose of theophylline, however, is many times greater than the levels attained from caffeine metabolism.
Each of these metabolites is further metabolized and then excreted in the urine.