I almost started another thread about this because it might not fit into the scope the original poster had in mind, but it seems to fit with what others are taking about so I'm putting it here.
I have golfed most of my life with a 2 piece ball... or whatever I found on the course. To be honest I was never that serious about golf. I played it and enjoyed it but never put the effort into getting any better at it. I would play for a while then put it down for a few years then pick it back up again. The 2 piece ball was fine for me and to tell you the truth I never noticed much of a difference between any of them besides maybe a little softer feel of some of them.
I picked golf back up this year, but this time I was serious about getting better and finally being able to play to my potential. I'm still only about a bogey player but feel like I am getting better now that I am learning the right way to do things. I hit the ball fairly far and fairly straight off the tee but have struggled to keep the ball on the green. That said I have been doing a lot of research on balls. More than I would like to admit. I realized that maybe a 2 piece ball is not for me. I wanted to be able to stop better on the green so I wanted to go for a 3 piece with a urethane cover and a soft layer underneath to get a little better spin on the greens. After a lot of research I decided to try the Maxfli Tour. Mostly because of the cost vs performance aspect and it got good reviews. I can tell a difference on the greens. It is definitely better but I lost a little control with my drives. I hit it far and kind of straight but see more of a difference than I would like. Then I found a Divide someone lost and decided to give it a try. I think this is my Goldilocks ball at this point in my game. It is the Srixon Q-star Tour. It has the 3 piece advantages that I want but with a little lower compression (72 vs 85) it seems straighter off the tee and still gets good distance with my swing speed.
The bottom line is if you have a slow swing speed and not good control over your drives a 2 piece ball is absolutely the way to go but there will (hopefully) come a time as you progress and get better that you will need to upgrade your ball. I think most golfers are still at that 2 piece ball stage. I can hit them long and straight, but at this point in my game the most important thing for me is stay on the green. Hopefully soon the Maxfli Tour will be my go to ball.